Beckman Coulter, pionir analitik sejak 1935, kini bagian dari Danaher. Dengan warisan inovasi dan 12.000+ talenta global, mereka mendefinisikan ulang teknologi laboratorium modern.
2025
Cell Health Centrifugation Flow Cytometry Genomics Liquid Handling Particle Analysis
AAV Analysis with AUC
Centrifugation
Optima X-Series - Floor-Standing Ultracentrifuges Our Optima XPN/XE ultracentrifuges provide speeds to 100,000 rpm (802,000 x g) and offer intuitive operation coupled with powerful onboard features such as eXPert software for method development. They can be added to your network. You can also enable VNC (Virtual Network Connection) or API (Application Programming Interface) to allow the system to receive instructions from a remote application (Optima XPN only). Need for High-resolution AAV Analysis AAVs are well-known as having variability in the amount of genetic load in the particles, where only those containing the full gene insert can elicit the desired function. Thus, AAV purification to isolate only the full particles is critical. Further, characterizing the ratio of functional (full) and non-functional (empty/partial) particles is paramount to optimize culture productivity and understand production consistency, establish dosing, and ensure patient safety.
Empty
Type 45 Ti 6 x 94 mL
Partial
Full
• Rotor volumes up to 1675 ml • Offers the capability to support 21 CFR Part 11 (only Optima XPN) • Variety of swinging-bucket, fixed-angle, vertical, near-vertical and zonal rotors Solution Air Bottom Meniscus
• Exclusive s afety concept with Rotor-Safety- System, Dynamic Rotor Inertia Check (DRIC) • Innovative concept for the management of voltage fluctuations and power failures • BioSafe*-Concept for laboratory ware, rotor and centrifuge
SW 32 Ti 6 x 38.5 mL AUC: A Unique Characterization Technique Analytical ultracentrifugation (AUC) is a unique approach for particle separation and characterization. With AUC, particles are often separated by varying sedimentation coe " cient (S) – a collection of size, mass, shape, and density. Because AAV particles of varying load di ! er in mass and density, AUC excels at providing high-resolution data for analysis of such particles in solution, without the need or possible side e ! ects of matrix interactions. VTi 50.1 12 x 39 mL
ω
MLA-150 8 x 2 mL
Buoyant force
Optima MAX-Series - Tabletop Ultracentrifuges The Optima MAX-Series generates speeds of up to 150,000 rpm with rcf of over 1 million x g. With an extended volume range, these space-saving tabletop ultracentrifuges are a perfect alternative to floor standing centrifuges. Direction of Sedimentation Frictional force Centrifugal force r = 0 x
r
y
• Sample volumes from 100 μ l - 194.4 ml • BioSafe*-Concept for laboratory ware, rotor and centrifuge
• MAX-XP software enables extended safety concept (user login, password)
MLA-55 8 x 13.5 mL
AUC Provides Higher-resolution Data AUC has become well-known as the gold standard for quantitative assessment of AAV particle quality and fullness. Compared to anion exchange chromatography (AEX), for example, AUC o ! ers much greater resolution and the clear identification of partials, where AEX falls short. These high-res AUC analyses are not only useful in final product
Optima AUC - Analytical Ultracentrifuges Analytical ultrac entrifugation is a versatile, rigorous and accurate technology available for determining the molecular
QC, but also in cell culture development to optimize for productivity of full particles. weight, hydrodynamic and thermodynamic properties of a protein or other macromolecule. AUC is a stand-alone, first-principle technique performed in a matrix-free environment that does not require standards. • Separation and optical measurement in one step • AUC enables the detection of even small amounts of sub-populations (down to even <1%) • With very few buffer constraints, AUC enables characterization of samples in their native state under biologically relevant solution conditions • Characterization of heterogeneous samples • AUC reliably detects low sub-populations, e.g. aggregation proportions of <1%
Analysis of empty (E), full (F), and partially-full (P) AAV particles with aggregates (X). Reproduced with permission from Wang et al. Analysis of empty (E), full (F), and partially-full (P) AAV particles with aggregates (X) via AEX (A) and AUC (B). Reproduced with permission from Wang et al.†
Summary AUC can provide high-resolution information on AAV samples, including opportunities to quantitatively identify empty, full, and partially-full particles along with aggregates. Click here to learn more about getting started with AUC and learn about the new features of the Optima AUC.
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*BioSafe and BioSafety are terms intended to describe the enhanced biocontainment features of our products. Product not for use in diagnostic or therapeutic procedures.
Mobile fuge The app that connects you to your centrifuge
Intelli fuge More than just a calculator for your rotors
More than just a rotor calculator.
visit becls.co/intellifuge
• Monitor and control up to 16 centrifuges • Warnings and status messages sent directly to your smartphone or tablet • Usable for Optima XPN- and Avanti-JXN series
• Easily convert between rotors and tubes • Direct overview of all available rotor and tube combinations • Comparison of different rotors/tubes
Avanti JXN-Series - High Performance Centrifuges The Avanti JXN-Series centrifuges are versatile tools for a wide range of separations. This lab equipment is designed to provide more throughput, faster turns, and greater control over workflows. Speeds are available to 30,000 rpm (110,500 x g) and volumes to 6 liters, offering diverse solutions to separate cells, extracellular vesicles, proteins and nanoparticles. • BioSafe*-concept for centrifuge, rotor and labware
JA 30.50 8 x 50 mL
• Existing rotor portfolio that is optimized for efficienct harvesting and improved sample clarification
• Many user management functions available to overcome shared lab challenges, like VNC (Virtual Network Connection) or API (Application Programming Interface) GMP supporting tools Tabletop Centrifuges Designed for cell culture processing, blood sample preparation, microplate applications and more. Our benchtop centrifuges provide fast and efficient centrifugation solutions for
JLA 12.500 6 x 500 mL
JLA 8.1000 6 x 1000 mL
Ultracentrifugation Labware and Reagents • A large choice of standard and sterile tubes (vials), tube closure systems and reagents are available • NEW: OptiMATE Density Gradient Reagents are shelf-stable, cGMP-supporting, highly concentrated solutions with specified concentration, density, refractive index, sterility, endotoxin levels, and 18-month shelf life.
Microfuge-Series – Microcentrifuges Small, quick and versatile. Centrifuge s from our Microfuge-Series are designed for 1.5 and for 2 ml microcentrifuge tubes (vials) for PCR-tubes (vials). your lab in a single, compact instrument. • The Avanti J-15-series instruments use the Ultra Harmonic Technology (UHT) for an optimized deceleration phase • Benchspace-saving models available (our 1.6L instrument is just 46cm wide , our 3L instrument just 60.5cm)
Selection of ultracentrifugation tubes
Open-Top Round Bottom Ultra-clear
Bottle and Cap Assembly Polycarbonate
Open-Top konical Polypropylene
Quick-Seal Round Bottom Polypropylene
Quick-Seal Round Bottom Ultra-Clear
OptiSeal Round Bottom Polypropylene
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*BioSafe and BioSafety are terms intended to describe the enhanced biocontainment features of our products.
Clinical Flow Cytometry
CellMek SPS - Sample Preparation System The next level of sample preparation for flow cytometry laboratories. True walk-away automation of complex methods • Design your own protocols including staining, lysing, and cell washing for a variety of specimen types and applications in clinical flow cytometry. • Frees up time with an automated end-to-end sample preparation with on-demand processing for continuous loading and unloading (no batching required)
DxFLEX** - Flow Cytometer Add more colors without adding more concerns.
Simplify your leukemia and lymphoma diagnostics*** with the ClearLLab 10C system.
High-complexity testing made easy • Simplified compensation procedure (gain-independent compensation) • More information per tube with up to 13 colors**
Advanced sensitivity and resolution • Separation of dim populations • Easier and more robust gating
Compact design • Saves lab space • No compressor cart
Navios EX* - Flow Cytometer Reliable, accurate, efficient. Based on proven Navios design • Up to 10 colors* • Enhanced resolution to distinguish a wide range of populations • IVD Assays for lymphocyte subset and Leukemia & Lymphoma Analysis***
AQUIOS CL - Load & Go Cytometer Fully automated flow cytometer with integrated sample preparation for low-complexity assays.
IVD Assay • Intuitive lymphocyte subset analysis • Fully automated ISHAGE-compliant stem cell analysis
Automation of sample preparation • Load primary samples, and receive results • Performs the entire preparation process • Simultaneous sample preparation and acquisition for optimized time to result
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* Navios EX is CE marked for 10-color in-vitro diagnostic use. In U.S., Navios EX is intended for use as an in vitro diagnostic device for immunophenotyping with Navios tetra software and CYTOSTAT tetraCHROME reagents and ClearLLab 10C system. All other uses are for research use only. ** In the US, DxFLEX flow cytometer is cleared for 10-color in vitro diagnostic use with ClearLLab 10C Reagent System. Fluorescence channels FL 11-FL13 and all other applications are for Research Use Only. *** Non-Hodgkin‘s Lymphoma only.
Research Flow Cytometry
CytoFLEX** SRT - Benchtop Cell Sorter Sort up to four cell populations at the same time with simple compensation workflow and the ability to upgrade your cell sorter to meet new requirements at any time.
• 4-way mixed-mode sorting with the ability to capture soft aborts • Up to 4 lasers and 15 fluorescence detectors - easy to upgrade • Simple compensation workflow thanks to APD Technology • Cell sorting in 96- or 384-well plates with index sorting capability
CytoFLEX** - Platform ... optimally combines excitation and emission, thereby achieving maximum sensitivity. Detection of extracellular vesicles; Measurement of bacteria, bacteriophages, yeasts, cells or similar can be easily realized. With up to 6 lasers and up to 21 fluorescence avalanche photodiodes (plus 2 scatters) this system leaves nothing to be desired. • Compact bench top flow cytometer • Easy-to-use, intuitive software and compensation • Single sample feed and Multi-Plate Loader Module options
• Absolute cell count without reference beads • 30,000 events per second, 24 bit, 7 decades
CytoFLEX nano** - Flow Cytometer The CytoFLEX nano Flow Cytometer is the first nanoscale flow cytometer that enab les you to simultaneously detect particles as small as 40 nm † and characterize particles with precision thanks to its 6 channels of fluorescent measurement and ability to count via volumetric delivery. We know flow cytometry can be complex. With a workflow-focused software and complementary suite of reagents, the CytoFLEX nano Flow Cytometer has been created with user accessibility and data quality in mind, so you can focus on creating meaningful results.
NEW
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** For Research Use Only. Not for use in diagnostic procedures. † polystyrene when triggering on violet side scatter
Flow Cytometry Reagents
DURAClone** - Kits DURAClone* kits are dry antibody panels formulated ready-to-use as single tests in FACS tubes, delivering uncompromised performance as compared to liquid reagents. The elimination of antibody pipetting fosters standardization, productivity and method transferability, covering a broad range of immune phenotyping and functional assays.
+
+
• Reduction of human sources of error and variability • Streamlined workflows with reduced hands-on time • Storage and shipping at room temperature • Simplified inventory management • Ideal for longitudinal and multicentric studies
Take dry unitized dried-down reagent tube
Add blood sample
Vortex & incubate
Add lysis solution & incubate
Acquire & analyze by flow cytometry
RESOURCE* - Contract Manufacturing Services Beckman Coulter manufactures the components for your specific test reagents under GMP conditions, according to your specifications. LUCID** - Custom Design Service With this service, almost all products of our catalogue, but also one’s own antibodies, or those acquired from other manufacturers, can be manufactured to customer specifications, including configuration, conjugation, and quantities. • Production of large quantities • Conjugation of customer‘s own antibodies and multicolored cocktails • All products also available as DURAClone • Long shelf-life at RT, ideal for clinical research trials and multicenter studies
LUCID Custom Panel Design & Cocktail Services
Contract Manufacturing Services
Integrated L&L # solution for Immunophenotyping and analysis for lymphoid and myeloid neoplasms ClearLLab 10C are in-vitro diagnostic tests for qualitative identification of cell populations with multiparameter Immunophenotyping using DxFLEX, Navios EX and Navios flow cytometers. • Fou r ready-to-use 10-color panels in a dried format (B, T, M1 & M2 Tubes) • Cellular process controls (normal/abnormal) • Simplified analysis with predefined Kaluza C protocols and templates • Including a casebook for training of staff
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* For CMS/RESOURCE reagents, the customer is the legal manufacturer of the product. The customer provides the formulation of the reagent combination and bears responsibility for any legal or regulatory requirements for the finished product including validation, product label content, intended use claims and regulatory approvals or clearances based on the product’s final use. ** For Research Use Only. Not for use in diagnostic procedures.
Flow Cytometry Software
Radarplot
Software Solutions If you are looking for clinical analysis s oftware to cover your routine data analysis, or for a more advanced solution for your cytometry research, we have the right solution for you.
ViSNE
Bild 1
**
Cloud-based Cytobank** software for data analysis enables comprehensive visualization and analysis of single-cell data with no need for coding knowledge:
• Integrated algorithms for dimensionality reduction, unsupervised clustering and biomarker discovery • Built-in statistical tools • Automated gating option
CD4 T cells
Kaluza C - Clinical Analysis Software Protects your data and your reputation Designed for the needs of clinical labs • LIS connectivity • QC module
Bild 2
B cells
Easy to learn, easy to use • Platform-agnostic • Intuitive, user-friendly interface
Get more information out of your data • Full suite of analysis and statistical tools • Exclusive display options for multi-parametric data and rare events
• Compare reports • Electronic sign off
Monocytes
CD8 T cells
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** For Research Use Only. Not for use in diagnostic procedures. # For lymphoma this refers to Non-Hodgkin’s lymphoma only.
Confidential - Company Proprietary
Cell Health
Cydem VT Automated Clone Screening System The Cydem VT system provides the ability to screen a la rger number of clones with the convenience of unattended operation for up to three days. By harnessing the power of automation, it fills a critical gap by delivering
valuable insights. The system screens clones under conditions that closely mimic biomanufacturing production, while continuously gathering essential data on cell growth and productivity. • High-throughp ut clone screening in cell line development
NEW
• Automated, walk-away operation • Cultivation of 96 parallel clones • On-deck cell density/viability and antibody titer analysis
• Fully integrated system • All results in one software
Vi-CELL BLU Cell Viability Analyzer The Vi-CELL BLU is a fully automated and fast solution analyzer for your sample processin g, cell viability analysis and cell counting by automating the trypan blue method. The instrument offers enhanced benefits and supports you with reliable data when making decisions for your important projects.
• Increase throughput via fast processing t ime: 130 s • Strong instrument-to-instrument correlation for optimal data comparison across labs and sites • Flexible sample loading with 24-position carousel or 96-well plate
• Space savings • Easy-to-use reagent kit • Advanced automation option to introduce samples without human intervention
Vi-CELL MetaFLEX Bioanalyte Analyzer Fast and reliable analysis of bioanalytes in cell culture media with low sample volumes. The Vi-CELL MetaFLEX is the optimal solution for monitoring metabolic activities in a matter of seconds.
• Only 65 μ l sample volume required • Quick results in only 35 seconds
• Parameters: pH, glucose, pO 2
and pCO 2
, lactate, potassium, calcium, sodium
• Can interface with data management system
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* Product not for use in diagnostic or therapeutic procedures.
Cell Health
Valita Titer method
Valita Titer Assay High-throughput quantification of antibody titer. The Valita Titer assay is a rapid and easy method to determine IgG titer and can be integrated into a Biomek i-Series workstation for automation. • Takes less tha n 15 minutes • Available in 96- and 384-well plates • Automation friendly • Straight from culture to plates and results • Simple assay, just add, mix and measure in a microplate reader compatible with fluorescence polarization • Two detection ranges available: 2.5 – 100 mg/L or 100-2000 mg/L
Incubate for 5 minutes at room temperature
Measure IgG using FP on a plate reader
Add fresh media & IgG sample and mix
Valita Aggregation Pure Assay Simple and fast assay to accurately determine IgG aggregation and improve cell line and process development workflows. The Valita Aggregation Pure Assay enables high-throughput screening of antibody aggregation using fluorescence polarization. • Reliable results, comparable to HPLC-SEC and DLS quantification of aggregated proteins • Quick screening in 15 minutes • Coated 96-well plates to determine aggregation using a microplate reader and fluorescence polarization. • A utomatable with the Biomek i-Series Automated Workstation Fermentation
NEW
BioLector XT Microbioreactor Accelerate your biop rocess development with microbioreactors for high-throughput cultivations.
• Up to 48 simultaneous cultivations in a single microtiter plate • Suitable for aerobe and anaerobe fed-batch processes thanks to continuous, well-individual pH and feeding control • Customizable cultivation protocols, flexible combination of feeding and pH control strategies
• Cultivation of highly oxygen-demanding strains with gassing of up to 100 % oxygen • Can be automated for complex experiment design (DoE), sampling and more
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* Product not for use in diagnostic or therapeutic procedures.
Liquid Handling Tip-Based
Biomek i-Series Automated Workstation Engineered to optimize walk-away time in mid- to high-throughput labs.
• Onboard cameras provide live broadcast and on-error video capture enabling remote diagnostics and expediting service response • Rotating gripper with unique offset finger design optimizes access to high-density decks for more efficient workflows • Large-volume, 1mL multichannel head with selective tip pipetting • Multiple color- and pattern-coded status light bar instantly alerts you to the instrument’s current mode
Biomek i7 Automated Workstation • Large deck capacity with 45 positions allows full walk-away capability for complex protocols • Ultimate flexibility through combinations of multichannel head (96/384) and Span-8 with gripper • Modular deck allows third-party adaptation for changing workflows Biomek i5 Automated Workstation • 25 deck positi ons • Compact instrument with large deck capacity allows full automation in small lab spaces • On-deck device integrations for changing workflow needs • Available configurations: - Multichannel head (96/384) with gripper - Span-8 with gripper
Integrated Workstations Integration capabilities of the Biomek i-Series go beyond on-deck integrations.
The Biomek i-Series is designed to enable integration through the sides, rear and also beneath the instrument. We can transform Biomek liquid handlers into complete workflow solutions for your specific needs. From simple on-deck devices to complete robotic systems, we can develop custom, Biomek-based solutions that integrate third-party tools such as barcode readers, microplate centrifuges, plate readers and imagers, plate transportation devices, plate washers, safety and biocontainment enclosures, temperature controlled storage, tube handling/capping/decapping devices and many other related devices.
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Product not for use in diagnostic or therapeutic procedures.
Liquid Handling Acoustic Dispensing
Echo-Series - Acoustic Liquid Handler Non-contact, ultra-low-volume liquid transfers through sound energy. • Highly precise & fast - reduced cross-contamination risk • Fast „any-well-to-any-well“-transfers for performing highly complex, multi-component assays and experiments • Liquid transfer from Echo compatible microtiter plates in high throughput • Integrates with Biomek i-Series or Access - Robotic Systems
Echo 525 Series Liquid Handler • Tran sfers precise increments of 25nl droplets • Designed for use in genomic and biologic workflows • For aqueous reagents
Echo 650 Series Liquid Handler • Transfers precise incr ements of 2.5 nl • Designed for high-throughput workflows • Compatible with DMSO & aqueous fluids • T Models compatible with FluidX Acoustic tubes
Acoustic Droplet Ejection - The transducer is positioned below the
Access - Robotic Systems Ready-to-Go Robotic Systems for Echo Liquid Handlers • Modular design • Flexible solutions for integration of 1-12 devices • Environmental control options available
source microplate well and emits focused sound energy repeatably to the meniscus of the fluid to be transferred. A stream of 2.5 nL or 25 nL droplets (model dependent) is reliably ejected into a well of an inverted destination microplate. fluid types with a degree of flexibility and reliability not possible with traditional liquid handling technologies.
Inverted destination plate Inverted destination plate
FluidX™ Acoustic Sample Tubes - by Azenta Life Sciences, transform workflows by enabling acoustic dispensing directly from tubes. The AcoustiX™ Tube preserves sample integrity by allowing samples to be accessed individually – ideal for applications that require subsets of large libraries to be accessed frequently.
Source plate
2.5 nL or 25 nL droplet transfers 2,5 nl or 25 nl droplet transfers
Source plate
Fluid TYPE A Fluid TYPE B Fluid TYPE C Fluid TYPE D Fluid TYPE A Fluid TYPE B Fluid TYPE C Fluid TYPE D
Transducer (acoustic energy generator)
Echo® 650 (acoustic energy generator)
Acoustic Sample Tubes
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Product not for use in diagnostic or therapeutic procedures.
Liquid Handling Software
Biomek - Automation Control Software* Biomek software ensures that your samples are treated identically within every liquid transfer and in every run providing absolute confidence in your data. Biomek Software Method authoring with point-and-click interface Biomek Method Launcher Simplified, intuitive user interface for operators DART 2.0 Software Enables efficient management of data generated by your Biomek Workstation, between and across methods SAMI Workstation EX Software This flexible software package is designed to provide complete automation and process control supporting a wide variety of applications SAMI Process Management Software This calendar-format tool controls long processes such as cell culture within a single, visual workflow management tool
Echo - Automation Control Software Echo software application s utilize interactive wizards and graphics to simplfy creation of complex liquid transfer protocols for Echo systems.
Echo Software Applications Plate Reformat Quickly assemble assays with a variety of transfer functions to design custom layouts Cherry Pick Transfer from any well to any well using pick list files for rapid hit picking, sample pooling and more Combination Screen Design complex combination screening layouts Dose-Response Assemble dose-response curves of varying concentration range using direct dilution Plate Audit Analyze and monitor samples with acoustic analysis Plate Reformat Quickly assemble assays with a variety of transfer functions to design custom layouts Array Maker Graphically design custom spotting-patterns and formats
Tempo Automation Control Software Offers a research-friendly interface for scheduling Access Laboratory Workstation protocols. Interfaces directly with all compatible versions of Echo Software Applications.
Biomek Deck Inspection (DeckOptix TM )
SAMI Workstation EX Software
Biomek Method Launcher
Tempo Automation Control Software
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* Specific software products shown here are available for purchase as optional add-ons to the Biomek software that is provided at no additional cost with Biomek automated workstations.
Genomic Solutions
Biomek NGeniuS Next Gen Library Prep System
The Biomek NGeniuS System represents an evolutionary leap in NGS liquid handling with its best-in-class performance, error-reduction technology, ease-of-use, reduced
hands-on time, and flexibility. • Batch sizes of 4 to 24 samples
• Dynamic DeckOptix system provides software-guided labware placement and confirmation • Reagent carousel reduces the need to manually transfer reagents and automates most reagent kits designed for manual use • Complimentary Application Library is designed to evolve with your changing chemistry needs Biomek i5 Nucleic Acid Solutions We’ve combined our expertise in reagent chemistry and automation, providing you three configurations to suit increasing workflow complexity. This offers the benefits of a plug- and-play system with the ability to add components later for enhanced functionality.
• Biomek i5 Cleanup Solution • Biomek i5 Extraction Solution • Biomek i5 Advanced Extraction Solution
Kits
Our reagent portfolio is powered by SPRI technology, widely known for use in our AMPure XP reagent, which uses paramagnetic beads to selectively bind nucleic acids by type and size. SPRI enables our chemistries to deliver high-performance isolation, purification and cleanup protocols supporting applications such as qPCR, ddPCR, Sanger sequencing, next-generation sequencing (NGS) and microarrays.
DNA Isolation Kits • Apostle MiniMax - cfDNA from plasma and serum • DNAdvance gDNA from mammalian tissue and cells, saliva, Genotek Oragene and mouse tail • GenFind v3 - gDNA from whole blood, serum, mammalian tissue, cell culture, saliva, buccal swab, FTA cards, bacteria and fresh or frozen tissue • FormaPure XL Total - DNA and Total nucleic acid isolation from FFPE tissue • CosMCPrep - Plasmid DNA from E. coli
RNA Isolation Kit • RNAdvance Viral / RNAdvance Viral XP
Purification & Cleanup Kits • AMPure XP - Removal of primers, unincorporated dNTPs, primer dimers, salts and other contaminants • CleanSEQ - Removal of Big Dye terminator and sequencing reaction contaminants • RNAClean XP - Post-reaction cDNA and cRNA cleanup • SPRIselect - Fragment size selection for NGS library construction
• RNA from saliva or swab transport media samples • RNAdvance Blood - RNA from blood (PAXgene tubes), cells and tissue • RNAdvance Cell v2 - RNA from mammalian cell cultures (<50K cells) • RNAdvance Tissue - RNA from tissue and cells (50K to 1M cells) • FormaPure XL RNA- RNA from FFPE tissues
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Product not for use in diagnostic or therapeutic procedures. Biomek NGeniuS Next Generation Library Prep Systems and demonstrated applications are not intended or validated for use in the diagnosis of disease or other conditions.
Particle Analysis - Particle Size Analysis
Universal Liquid Module
LS 13 320 XR Particle Size Analyzer Laser diffraction at the highest level for precise particle size measurement in suspensions, emulsions and powders. The PIDS-Technology and the extended measuring range provide a higher resolution and more accurate, reproducible results. • Measuring range : 10 nm - 3,500 μ m • Detects down to 10 nm due to enhanced PIDS-Technology • High-resolution analysis through 132 detectors Multisizer 4e Coulter Counter • Flexible dispersion modules for suspensions (e.g. UL module) or powders (Tornado) • Simple software for data evaluation within a few clicks • Features support 21 CFR Part 11 compliance • Sub-visible particle counting
Dry Powder System Module
The Coulter Principle enables particle sizing and counting with the highest resolution. Thanks to the latest Digital Pulse Processor Technology the Multisizer 4e provides a detailed insight into possible subpopulations of the particle distribution. • Dynamic range: 2 – 80 % of the capillary opening (Standard: 2 – 60 %) • Features support 21 CFR Part 11 compliance • Independent of form, color, density, and optical properties Particle Analysis - Liquid Particle Counting • Measuring range: 0.2 μ m – 1,600 μ m (diameter) • Presentation of number, surface, and volume distribution (absolute, /ml, %)
HIAC 9703+ Liquid Particle Counter Designed specifically for GMP injectable and infusion testing, the HIAC 9703+ PharmSpec software provides automatic pass/fail reporting to USP, EP, JP and KP. Light Obscuration Testing to USP<787>, <788>, <789> and EP2.9.19 • Audit trail • Active Directory User Name and Password control • Database back-up and restore
• Secure electronic record export via Ethernet • Test to USP<787> with just 0.2 mL of product
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Particle Analysis - Cleanroom Environmental Monitoring
MET ONE 3400+ Portable Counter for Routine Environmental Monitoring
Designed for GMP Cleanroom routine environmental monitoring, the MET ONE 3400+ portable air particle counter allows users to upload their SOP maps onto the counter screen to create an interactive map for the technicians. • Audit trail • Active Directory User Name and Password control • Export secure electronic records straight from the counter via Wi-Fi or Ethernet MET ONE HHPC+ Handheld Air Particle Counters Handheld particle counter for cleanrooms and cleanroom applications. • Measuring range: 0.3 μ m – 10 μ m • Throughput should be sample volume of 2.83 l/min • Available with 2, 3 or 6 channels • Direct download of measured data in Excel via Ethernet or USB-Stick
MET ONE Cleanroom monitoring system Wall-mount air particle counters for cleanroom continuous monitoring systems. • 0.5- and 5-micron counter • Option for integral sampling pump • 24V DC or 100-230V AC power options
• Ethernet, Wi-Fi, RS485 and 4-20mA options • Built-in flow-rate monitor
Particle Analysis - WFI & PW Water Quality
PAT700 Total Organic Carbon and Conductivity Analyzer Designed specifically for Total Organic Carbon analysis (TOC) in Purified Water and Water for Injection. The PAT700 reports TOC, Conductivity (uncompensated) and Temperature for on-line monitoring to USP<643>, <645> and EP 2.2.38 and 2.2.44.
• Active Directory User Name and Password control • Automatic secure electronic record and audit trail daily export via Ethernet • System Suitability Test SOP routine built-in, with automated data entry and pass/fail calculation
• Reagent-free TOC analysis • 12 month service interval • Main and Standby, auto-switching UV lamps • No negative TOC results
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Product not for use in diagnostic or therapeutic procedures.
Contact us www.beckman.com
Beckman Coulter, Inc.
5350 Lakeview Parkway S Drive Indianapolis, IN 46268 United States
© 2025 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries.
ECHO is a trademark or registered trademark of Labcyte Inc. in the United States and other countries. Valita Titer, Valita Aggregation Pure and the ValitaCell logo are trademarks of ValitaCell Ltd. in the United States and other countries. Labcyte and ValitaCell are Beckman Coulter Companies. All other trademarks are the property of their respective owners.
2023-GBL-EN-104650-v2
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