Pharmaceutical Testing
Degassing
Used in combination with a vacuum pump, pressure meter and dissolved oxygen meter, the VDA system guarantees oxygen levels below 4 ppm, exceeding the recommendations set out in the pharmacopoeias (USP suggests an oxygen concentration <6 ppm is an adequate level of dissolution media deaeration). The Vacuum Deaeration Apparatus Model (VDA) from Copley is an easy-to-use and inexpensive unit designed to degas receptor medium prior to its use, ensuring that diffusion is unimpeded by the collection of gas beneath the membrane. Once deaerated, the system can be used to maintain the temperature of the degassed dissolution medium to the required temperature for testing.
• 500 mL pressure bottle containing receptor medium • Water bath to heat the contents of the bottle to 45°C • A magnetic stirrer/heater to stir the content of the bottle whilst heating it and the surrounding water bath • A condensate filter to prevent condensate from damaging the vacuum pump The VDA system comprises of: The following items are required in addition to provide a full system: • A vacuum pump • A differential pressure meter to display pressure and test for leaks • A dissolved oxygen meter to measure and display dissolved oxygen levels in the media
VDA
Cat. No.
Description
7291 7300 7903 7293 7294
Vacuum Deaeration Apparatus Model VDA IQ/OQ/PQ Documentation Pack for VDA Low Capacity Vacuum Pump Model LCP5
Digital Differential Pressure Meter
Dissolved Oxygen Meter
82
Powered by FlippingBook